Site na usoro arụ ọrụ ekwenyesiri ike, NMN bụ nke pụrụ icheebuba n'ime sel site na slc12a8 transporter na obere eriri afọ, ma na-abawanye ọkwa nke NAD + na akụkụ dị iche iche na anụ ahụ nke ahụ yana mgbasa ọbara.
Agbanyeghị, NMN na-emebi ngwa ngwa mgbe mmiri na okpomọkụ ruru ogo ụfọdụ. Ka ọ dị ugbu a, ọtụtụ NMN dị n'ahịa bụ capsules na mbadamba. Mgbe ị were NMN capsules ma ọ bụ mbadamba,Ọtụtụ n'ime ha na-eweda ala n'afọ, na naanị obere akụkụ nke NMN na-erute obere eriri afọ.
● Gịnị bụLiposomal NMN?
Liposomes bụ “akpa” dị okirikiri nke molekul dicyclic fatty acid a na-akpọ molecules phosphatidylcholine (phospholipids jikọtara na irighiri choline). Enwere ike iji "akpa" spherical liposome iji tinye ihe mgbakwunye nri dị ka NMN wee nyefee ha ozugbo n'ime sel na anụ ahụ.
Molecule phospholipid nwere isi hydrophilic phosphate na ọdụ ọdụ abuba hydrophobic abụọ. Nke a na-eme ka liposome bụrụ ihe na-ebu hydrophobic na hydrophilic ogige. Liposomes bụ vesicles lipid mere nke phospholipids jikọtara ọnụ iji mepụta akpụkpọ anụ okpukpu abụọ, dịka ihe fọrọ nke nta ka ọ bụrụ akpụkpọ anụ cell niile dị na ahụ anyị.
● Olee otúNMNna-arụ ọrụ n'ime ahụ?
N'ime usoro mbụ nke njikọ liposome-cell,NMN liposome na-arapara n'elu cell. N'ime njikọ a, NMN liposome na-abanye n'ime cell site na usoro endocytosis (ma ọ bụ phagocytosis).Site na mgbaze enzymes n'ime sel,A na-ewepụta NMN n'ime cell, iweghachi ọrụ nri mbụ.
Ebumnuche nke iji mgbakwunye ọ bụla bụ iji hụ na ọ na-abanye n'ọbara site na akpụkpọ anụ mucous na sel epithelial intestinal. Agbanyeghị, n'ihi nnabata nnabata dị ala yana bioavailability nke ụdị NMN ọdịnala,ihe na-arụ ọrụ na-efunahụ ike ya ka ọ na-agafe na tract digestive, ma ọ bụ na eriri afọ anaghị etinye ya ma ọlị.
Mgbe ejikọtara NMN na liposome, ọ na-akawanye mma maka njem NMN na bioavailability na-abawanye nke ukwuu.
Nbufe ezubere iche
N'adịghị ka usoro nnyefe morphological ndị ọzọ NMN,Liposomal NMNnwere ọrụ ntọhapụ egbu oge, nke na-abawanye oge mgbasa ozi nke isi ihe na-edozi ahụ n'ọbara ma na-eme ka bioavailability dịkwuo mma.
Ka elu bioavailability nke ihe na-arụ ọrụ, otú ahụ ka mmetụta ya na-adị n'ahụ.
Mmụba dị elu
Liposome NMNa na-etinye obi gị dum site na usoro lymphatic n'ime mkpuchi mucosal nke ọnụ na eriri afọ,na-emebi metabolism nke mbụ na ire ere na imeju,n'ịhụ na nchekwa nke liposome NMN iguzosi ike n'ezi ihe. A na-eme synthesis iji mee ka NMN dị mfe ibufe na akụkụ dị iche iche.
Mmụba nke a dị elu pụtara nrụpụta dị elu yana obere doses maka nsonaazụ kacha mma.
Biocompatibility
Achọpụtara na membranes cell n'ime ahụ niile, phospholipids na-adị n'okike, ahụ na-amatakwa ha dị ka ndị kwekọrọ na ahụ ma ghara ịhụ ha dị ka "nsi" ma ọ bụ "ndị mba ọzọ" - ya mere,anaghị ebuso ọgụ ọgụ megide liposomal NMN.
Ikpuchi ihu
Liposomeschebe NMN ka ọ ghara ịchọpụta site na usoro ahụ ji alụso ọrịa ọgụ,iṅomi biofilms na inye ihe na-arụ ọrụ oge karịa ka ọ rute ebe ọ na-aga.
Phospholipids na-ekpuchi ihe ndị na-arụ ọrụ ka ha wee nwee ike itinye uche karịa ma gbanahụ ọrụ nhọrọ nke eriri afọ.
Gafee ihe mgbochi ụbụrụ ọbara
E gosiputara liposomesgafere mgbochi ọbara-ụbụrụ, na-enyere liposomes aka itinye NMN ozugbo n'ime sel ma kwalite mgbasa ozi na-edozi ahụ site na usoro lymphatic.
● NEWGREEN na-eweta NMN ntụ ntụ/Capsules/Liposomal NMN
Oge nzipu: Ọktoba 22-2024