Liposomal Berberine Newgreen nlekọta ahụike mgbakwunye 50% Berberine Lipidosome ntụ ntụ
Nkọwa ngwaahịa
Berberine (Berberine Hcl) bụ alkaloid sitere n'okike nke dị n'ọtụtụ ebe n'ụdị osisi dị iche iche ma nwee mmetụta dị iche iche nke ọgwụ, dị ka antibacterial, mgbochi mkpali, hypoglycemic na mmetụta na-ebelata lipid. Ịkwado berberine na liposomes na-eme ka bioavailability na nkwụsi ike ya dịkwuo mma.
Usoro nkwadebe nke berberine liposomes
Ụzọ ihicha ihe nkiri dị mkpa:
Gbanyụọ berberine na phospholipids n'ime ihe mgbaze organic, kupụ ka ọ bụrụ ihe nkiri dị mkpa, wee tinye usoro mmiri mmiri wee kpalite ka ọ bụrụ liposomes.
Ultrasonic usoro:
Mgbe hydration nke ihe nkiri ahụ gasịrị, a na-anụcha liposomes site na ọgwụgwọ ultrasonic iji nweta ihe ndị dị n'otu.
Ụzọ homogenization nrụgide dị elu:
Gwakọta berberine na phospholipids ma mee oke nrụgide homogenization iji mepụta liposomes kwụsiri ike.
COA
| Ihe | Nkọwapụta | Nsonaazụ |
| Ọdịdị | Yellow mma ntụ ntụ | Kwado |
| berberine (assay) | ≥50.0% | 50.31% |
| Lecithin | 40.0 ~ 45.0% | 40.0% |
| Beta cyclodextrin | 2.5-3.0% | 2.8% |
| silicon dioxide | 0.1-0.3% | 0.2% |
| Cholesterol | 1.0 ~ 2.5% | 2.0% |
| Berberine lipid | ≥99.0% | 99.18% |
| Ọla dị arọ | ≤10ppm | <10ppm |
| Ọnwụ na ihicha | ≤0.20% | 0.11% |
| Mmechi | A na-eme ya na ọkọlọtọ. | |
| Nchekwa | Chekwaa n'ebe dị jụụ na nkụ, zere ọkụ siri ike na okpomọkụ. Na-echekwa na +2°~ +8° ogologo oge. | |
| Ndụ nchekwa | Afọ 2 mgbe echekwara nke ọma | |
Ọrụ
Melite bioavailability:
Liposomes nwere ike ịbawanye ọnụego nnabata nke berberine nke ukwuu, na-eme ka ọ dịkwuo irè n'ime ahụ.
Chebe ihe ndị na-arụ ọrụ:
Liposomes na-echebe berberine site na oxidation na mmebi, na-agbatị ndụ ya.
Nbufe ezubere iche:
Site n'ịgbanwe njirimara nke liposomes, enwere ike nweta nnyefe ezubere iche na sel ma ọ bụ anụ ahụ.
Belata mmetụta ndị ọzọ:
Ihe mkpuchi liposome nwere ike belata iwe nke berberine na eriri afọ ma belata mmetụta ndị nwere ike ime.
Ngwa
Ngwaahịa ahụike:
Maka ojiji na ihe mgbakwunye nri iji kwado ahụike metabolic na njikwa shuga ọbara.
Nnyefe ọgwụ:
N'ihe gbasara biomedicine, a na-eji ya dị ka onye na-ebu ọgwụ iji kwalite nrụpụta berberine.
Ngwaahịa mara mma:
Ejiri ya na ngwaahịa nlekọta anụ ahụ iji nyere aka melite ahụike anụ ahụ ma nwee mmetụta mgbochi mkpali na antioxidant.
Nnyocha na mmepe:
Na nyocha ọgwụ na biomedical, dị ka ụgbọ ala maka ịmụ berberine.
Ngwungwu & Nbunye
